yplP [2018-11-23 15:36:48]

transcriptional activator (for SigL-dependent promoter)

locus: BSU21780

pI: 9.30

mw: 37.05 kDa

protein length: 331 aa

gene length: 993 bp

function: required for survival at low temperatures

product: transcriptional activator (for SigL-dependent promoter)

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.5|Cold stress proteins]

Gene

Coordinates: 2,294,286 → 2,295,281

Phenotypes of a mutant

• The mutant is cold-sensitive [http://www.ncbi.nlm.nih.gov/sites/entrez/16585774 PubMed]

The protein

Protein family

• [SW|Transcription factors activating transcription at SigL-dependent promoters]

Expression and Regulation

Operons

• genes: [gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]-[gene|8C382ECBEE4E2911E0233E0882BEA754156B9D40|yplQ]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-A896 (yplP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/896 NBRP B. subtilis, Japan]
• GP2304 ( ''yplP''::aphA3), available in [SW|Jörg Stülke]'s lab
• BKE21780 (Δ[gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTGGCTCCTTTTGG, downstream forward: _UP4_TAGCGATCGAAAGGAGAATG
• BKK21780 (Δ[gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTGGCTCCTTTTGG, downstream forward: _UP4_TAGCGATCGAAAGGAGAATG

References

• 16585774,12399512,21906631